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Structure of 49773-20-8
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2-(Methylsulfonyl)-ethanamine features a sulfonamide group flanked by a methylene linker and a primary amine, delivering enhanced solubility and metabolic stability. This polar, bench-stable derivative serves as a key scaffold in bioactive molecule design, particularly for targeting protein-ligand interactions in medicinal chemistry applications.
2-(Methylsulfonyl)ethanamine serves as a versatile building block in medicinal chemistry, enabling the introduction of a polar, metabolically stable sulfonamide-linked ethylamine moiety. Its amine functionality facilitates straightforward derivatization via alkylation, acylation, or coupling reactions, while the methylsulfonyl group provides enhanced solubility and hydrogen-bonding capacity. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis campaigns in API development.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: