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CS-W001157 4
Total: USD 88.00

2(5H)-Furanone

  • CAS No. 497-23-4

  • Cat. No. CS-W008270
  • Purity≥98%
  • MDL No.MFCD00005376

*For research and further manufacturing use only, not for direct human use.

2(5H)-Furanone|CS-W008270

Structure of 497-23-4

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General Information

  • CAS No. 497-23-4
  • Cat. No. CS-W008270
  • Purity ≥98%
  • MDL No. MFCD00005376
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄O₂
  • Molecular Weight 84.07
  • Synonym(s) γ-Crotonolactone
  • SMILES O=C1OCC=C1

Description

Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5H)-furanone (-crotonolactone) to pyrrolidine. The quorum sensing inhibition activity by 2(5H)-furanone was studied using bioindicator strains.2(5H)-Furanone (-Crotonolactone) has been used in: synthesis of (+)-L-733,060, (+)-CP-99,994 and (2S,3R)-3-hydroxypipecolic acidsynthesis of 5-substituted 2(5H) furanones (-butenolides) via direct aldol reaction with aromatic aldehydes catalyzed by bifunctional aminothiourea and aminosquaramide organocatalystsMichael addition reactions for synthesis of lignans three-component Michael-Aldol reactions with an aldehyde anda thiolate or carbanion

Synthesis

  • Route1
    • null|null
      201230-82-2
    • null|null
      37428-57-2
    • ~74%
    • In-stock
      2(5H)-Furanone|CS-W008270
      497-23-4

    References

    • Cowell,A.; Stille,J.K. Journal of the American Chemical Society, 1980 , vol. 102, p. 4193
  • Route2
    • null|null
      201230-82-2
    • null|null
      74-86-2
    • ~53%
    • null|null
      96-48-0
    • In-stock
      2(5H)-Furanone|CS-W008270
      497-23-4

    References

    • BASF Aktiengesellschaft Patent: US6346629 B1, 2002 ; Location in patent: Page column 5 ;
  • Route3
    • null|null
      98-01-1
    • ~65%
    • In-stock
      2(5H)-Furanone|CS-W008270
      497-23-4

    References

    • Poskonin Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 10 p. 1177 - 1183

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.0994
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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