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CS-W001157 4
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Carbohydrazide

  • CAS No. 497-18-7

  • Cat. No. CS-0149890
  • Purity≥98%
  • MDL No.MFCD00007591

*For research and further manufacturing use only, not for direct human use.

Carbohydrazide|CS-0149890

Structure of 497-18-7

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General Information

  • CAS No. 497-18-7
  • Cat. No. CS-0149890
  • Purity ≥98%
  • MDL No. MFCD00007591
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula CH₆N₄O
  • Molecular Weight 90.08
  • Synonym(s) cardonic dihydrazide; Carbohydrazide
  • SMILES NNC(NN)=O

Description

SPDP-Gly-Pro-NHS ester is a linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds.

Synthesis

  • Route1
    • null|null
      105-58-8
    • ~81%
    • In-stock
      Carbohydrazide|CS-0149890
      497-18-7

    References

    • Chandra, Ramesh; Kapoor, Ramesh N. Revue Roumaine de Chimie, 1992 , vol. 37, # 10 p. 1125 - 1132
  • Route2

    References

    • Yutilov, Yu.M.; Smolyar, N.N. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 8 p. 926 Khimiya Geterotsiklicheskikh Soedinenii, 1986 , # 8 p. 1136
  • Route3

    References

    • Li, Zheng; Zhu, Wei; Yu, Jinlan; Ma, Xuelin; Lu, Zhong; Xiao, Shuxiu Synthetic Communications, 2006 , vol. 36, # 18 p. 2613 - 2619

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H319-H412
Precautionary Statements : P261-P264-P270-P272-P273-P280-P301+P310-P302+P352-P305+P351+P338-P330-P337+P313-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   93.17
  • LogP   -1.967
  • H_Acceptors   3
  • H_Donors   4
  • Rotatable_Bonds   0

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