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CS-W001157 4
Total: USD 88.00

7-Chloroquinaldine

  • CAS No. 4965-33-7

  • Cat. No. CS-W020576
  • Purity≥98%
  • MDL No.MFCD00075436

*For research and further manufacturing use only, not for direct human use.

7-Chloroquinaldine|CS-W020576

Structure of 4965-33-7

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General Information

  • CAS No. 4965-33-7
  • Cat. No. CS-W020576
  • Purity ≥98%
  • MDL No. MFCD00075436
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈ClN
  • Molecular Weight 177.63
  • Synonym(s) 7-Chloro-2-methyl-quinoline
  • SMILES CC1=NC2=CC(Cl)=CC=C2C=C1

Description

7-Chloroquinaldine is a chlorinated quinoline derivative featuring a chlorine substituent at the 7-position, enhancing its electron-deficient character. This structural motif enables efficient incorporation into transition metal-catalyzed coupling reactions and facilitates functionalization in synthetic organic chemistry. The compound exhibits robust stability under standard conditions, simplifying handling and integration into multi-step synthesis workflows.

Application

7-Chloroquinaldine serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the quinoline core for pharmaceutical and agrochemical development. Its chloro substituent provides a reliable handle for palladium-catalyzed cross-coupling reactions, while the nitrogen-containing scaffold offers orthogonality for sequential transformations. Bench-stable and readily purified, it functions effectively in standard synthetic workflows requiring regioselective derivatization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.19662
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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