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CS-W001157 4
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1-Methyl-1H-pyrazolo[4,3-c]pyridin-4-amine

  • CAS No. 494767-19-0

  • Cat. No. CS-0052462
  • Molecule weight148.17
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-pyrazolo[4,3-c]pyridin-4-amine|CS-0052462

Structure of 494767-19-0

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General Information

  • CAS No. 494767-19-0
  • Cat. No. CS-0052462
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₄
  • Molecular Weight 148.17
  • Synonym(s) 1H-Pyrazolo[4,3-c]pyridin-4-amine,1-methyl-(9CI)
  • SMILES CN1N=CC2=C1C=CN=C2N

Description

1-Methyl-1H-pyrazolo[4,3-c]pyridin-4-amine is a bench-stable heterocyclic amine featuring a fused pyrazolopyridine core with enhanced solubility and electronic properties. This nitrogen-rich scaffold integrates readily into medicinal chemistry libraries, serving as a key building block for kinase inhibitors and bioactive small molecules.

Application

1-Methyl-1H-pyrazolo[4,3-c]pyridin-4-amine serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its fused pyrazolo-pyridine core provides enhanced metabolic stability and favorable binding interactions in target-directed compound libraries. The amine functionality enables straightforward derivatization via acylation, alkylation, or Suzuki coupling, while the methyl group improves solubility and reduces susceptibility to oxidation. Bench-stable and readily purified by standard chromatography, it functions effectively in multi-step synthetic sequences requiring robust, functional group-tolerant scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   56.73
  • LogP   0.5505
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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