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CS-W001157 4
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(5-(tert-Butyl)-1H-pyrazol-3-yl)methanol

  • CAS No. 493038-53-2

  • Cat. No. CS-0173199
  • Purity≥97%
  • MDL No.MFCD16620642

*For research and further manufacturing use only, not for direct human use.

(5-(tert-Butyl)-1H-pyrazol-3-yl)methanol|CS-0173199

Structure of 493038-53-2

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General Information

  • CAS No. 493038-53-2
  • Cat. No. CS-0173199
  • Purity ≥97%
  • MDL No. MFCD16620642
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄N₂O
  • Molecular Weight None
  • Synonym(s) (5-tert-Butyl-1H-pyrazol-3-yl)-methanol
  • SMILES OCC1=NNC(C(C)(C)C)=C1

Description

This pyrazole derivative features a tert-butyl group that imparts steric bulk and enhanced stability, while the pendant hydroxymethyl moiety enables straightforward functionalization. The scaffold integrates readily into bioactive molecule design, offering a robust platform for medicinal chemistry applications.

Application

(5-(tert-Butyl)-1H-pyrazol-3-yl)methanol serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-based scaffolds through standard functional group transformations. The pendant alcohol facilitates derivatization via esterification, etherification, or oxidation to aldehyde, while the tert-butyl group enhances steric stability and metabolic resistance. Its bench-stable nature and compatibility with common coupling reactions make it a practical choice for library synthesis and target-oriented compound development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   1.1995
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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