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CS-W001157 4
Total: USD 88.00

4-Hydroxy-3,5-dimethylbenzoic acid

  • CAS No. 4919-37-3

  • Cat. No. CS-W017872
  • Purity≥98%
  • MDL No.MFCD00016536

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-3,5-dimethylbenzoic acid|CS-W017872

Structure of 4919-37-3

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General Information

  • CAS No. 4919-37-3
  • Cat. No. CS-W017872
  • Purity ≥98%
  • MDL No. MFCD00016536
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight None
  • Synonym(s) 4-Hydroxy-3,5-Dimethylbenzoic
  • SMILES CC1=CC(=CC(C)=C1O)C(O)=O

Description

4-Hydroxy-3,5-dimethylbenzoic acid features a sterically hindered aromatic core with complementary hydroxyl and carboxylic acid functionalities. This configuration enables direct coupling in peptide synthesis and facilitates derivatization for bioconjugation. The molecule exhibits enhanced solubility in organic solvents and stability under standard bench conditions.

Synthesis

  • Route1
    • null|null
      124-38-9
    • In-stock
      4-Iodo-2,6-dimethylphenol|CS-W010226
      10570-67-9
    • ~39%
    • In-stock
      4-Hydroxy-3,5-dimethylbenzoic acid|CS-W017872
      4919-37-3

    References

    • Lu, Yixin; Lum, Tze Keong; Augustine, Yoon Wui Leow; Weltrowska, Grazyna; Nguyen, Thi M.-D.; Lemieux, Carole; Chung, Nga N.; Schiller, Peter W. Journal of Medicinal Chemistry, 2006 , vol. 49, # 17 p. 5382 - 5385
  • Route2

    References

    • Cheng, Lili; Aw, Carlin; Ong, Siew Siang; Lu, Yixin Bulletin of the Chemical Society of Japan, 2007 , vol. 80, # 10 p. 2008 - 2010
  • Route3
    • 4-Benzyloxy-3,5-dimethylbenzoic acid|CS-0196004
      97888-80-7
    • ~86%
    • In-stock
      4-Hydroxy-3,5-dimethylbenzoic acid|CS-W017872
      4919-37-3

    References

    • Bhalerao; Raju; Neelakantan Synthetic Communications, 1995 , vol. 25, # 10 p. 1433 - 1439

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.70724
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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