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CS-W001157 4
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Oxetan-3-amine hydrochloride

  • CAS No. 491588-41-1

  • Cat. No. CS-W018946
  • Purity≥97%
  • MDL No.MFCD09056831

*For research and further manufacturing use only, not for direct human use.

Oxetan-3-amine hydrochloride|CS-W018946

Structure of 491588-41-1

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General Information

  • CAS No. 491588-41-1
  • Cat. No. CS-W018946
  • Purity ≥97%
  • MDL No. MFCD09056831
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₈ClNO
  • Molecular Weight 109.56
  • Synonym(s) Oxetan-3-ylamine hydrochloride
  • SMILES NC1COC1.[H]Cl

Description

Oxetan-3-amine hydrochloride features a strained oxetane ring fused to a primary amine, enabling rapid bioconjugation under mild conditions. This bench-stable derivative delivers enhanced solubility and reactivity in aqueous media, facilitating efficient coupling with carboxylate and aldehyde functionalities. Ideal for linker design in antibody-drug conjugates and peptide synthesis.

Application

Oxetan-3-amine hydrochloride serves as a valuable building block in medicinal chemistry, enabling the incorporation of a strained, bioisostatic oxetane ring into target molecules. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, or coupling reactions. The hydrochloride salt enhances solubility and stability, supporting reliable handling and purification in standard synthetic workflows. This compound functions effectively in the construction of diverse heterocyclic scaffolds and drug-like architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   -0.2343
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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