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CS-W001157 4
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(R)-3-(3-Fluoro-4-iodophenyl)-5-(hydroxymethyl)oxazolidin-2-one

  • CAS No. 487041-08-7

  • Cat. No. CS-M1497
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-3-(3-Fluoro-4-iodophenyl)-5-(hydroxymethyl)oxazolidin-2-one|CS-M1497

Structure of 487041-08-7

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General Information

  • CAS No. 487041-08-7
  • Cat. No. CS-M1497
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉FINO₃
  • Molecular Weight 337.09
  • Synonym(s) (5R)-3-(3-Fluoro-4-iodophenyl)-5-hydroxymethyloxazolidin-2-one
  • SMILES FC1=C(I)C=CC(N2C[C@@](CO)([H])OC2=O)=C1

Synthesis

  • Route1

    References

    • DONG-A PHARM.CO.,LTD. Patent: WO2005/58886 A1, 2005 ; Location in patent: Page/Page column 24; 25 ;
  • Route2
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    • (R)-3-(3-Fluoro-4-iodophenyl)-5-(hydroxymethyl)oxazolidin-2-one|CS-M1497
      487041-08-7

    References

    • Im, Weon Bin; Choi, Sun Ho; Park, Ju-Young; Choi, Sung Hak; Finn, John; Yoon, Sung-Hwa European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1027 - 1039
  • Route3

    References

    • Im, Weon Bin; Choi, Sun Ho; Park, Ju-Young; Choi, Sung Hak; Finn, John; Yoon, Sung-Hwa European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1027 - 1039

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   1.7478
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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