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CS-W001157 4
Total: USD 88.00

4-Bromo-2,5-difluorophenol

  • CAS No. 486424-36-6

  • Cat. No. CS-0195276
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2,5-difluorophenol|CS-0195276

Structure of 486424-36-6

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General Information

  • CAS No. 486424-36-6
  • Cat. No. CS-0195276
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrF₂O
  • Molecular Weight 208.99
  • Synonym(s) QR BF EF DE
  • SMILES C1=C(C(=CC(=C1F)O)F)Br

Description

Fmoc-Lys (biotin-PEG4)-OH is a Lysine embedded biotin PEG linkers containing a carboxylic group and Fmoc-protected amine. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The Fmoc group can be deprotected under basic condition to release the free amine which can be used for further conjugations.

Synthesis

  • Route1

    References

    • WO2012/11125 A1, ; Page/Page column 154 ; WO 2012/011125 A1
  • Route2

    References

    • EP142328 B1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.4329
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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