Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Chloromethyl)-1H-benzo[d]imidazole

  • CAS No. 4857-04-9

  • Cat. No. CS-M0360
  • Purity≥95%
  • MDL No.MFCD00005602

*For research and further manufacturing use only, not for direct human use.

2-(Chloromethyl)-1H-benzo[d]imidazole|CS-M0360

Structure of 4857-04-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4857-04-9
  • Cat. No. CS-M0360
  • Purity ≥95%
  • MDL No. MFCD00005602
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇ClN₂
  • Molecular Weight 166.61
  • Synonym(s) NSC 15436; 2-(Chloromethyl)-1H-benzo[d]imidazole; 2-(Chloromethyl)benzimidazole; 2-Chloromethylbenzimidazole
  • SMILES ClCC1=NC2=CC=CC=C2N1

Description

2-(Chloromethyl)-1H-benzo[d]imidazole features a reactive chloromethyl handle attached to a rigid, electron-rich benzimidazole core. This combination enables efficient conjugation in synthetic transformations, particularly in the construction of bioconjugates and functionalized heterocycles under mild conditions. The moiety demonstrates stability during handling and compatibility with diverse reaction environments.

Application

2-(Chloromethyl)-1H-benzo[d]imidazole serves as a versatile bifunctional building block, enabling efficient incorporation of both imidazole and chloromethyl moieties into complex architectures. Its reactive chloromethyl group facilitates nucleophilic substitution under mild conditions, while the electron-rich imidazole ring enhances solubility and provides a handle for further derivatization. The compound exhibits excellent bench stability and compatibility with diverse functional groups, making it ideal for modular synthesis of bioactive heterocycles and pharmaceutical intermediates.

Synthesis

  • Route1
    • null|null
      79-11-8
    • null|null
      95-54-5
    • ~95%
    • In-stock
      2-(Chloromethyl)-1H-benzo[d]imidazole|CS-M0360
      4857-04-9

    References

    • Prousek, Josef Collection of Czechoslovak Chemical Communications, 1991 , vol. 56, # 6 p. 1358 - 1360
  • Route2
    • null|null
      105-39-5
    • null|null
      95-54-5
    • ~81%
    • In-stock
      2-(Chloromethyl)-1H-benzo[d]imidazole|CS-M0360
      4857-04-9

    References

    • Sheng, Chunquan; Che, Xiaoying; Wang, Wenya; Wang, Shengzheng; Cao, Yongbing; Yao, Jianzhong; Miao, Zhenyuan; Zhang, Wannian European Journal of Medicinal Chemistry, 2011 , vol. 46, # 5 p. 1706 - 1712
  • Route3
    • null|null
      79-04-9
    • null|null
      95-54-5
    • ~91%
    • In-stock
      2-(Chloromethyl)-1H-benzo[d]imidazole|CS-M0360
      4857-04-9

    References

    • Njoya, Yves; Boufatah, Narimene; Gellis, Armand; Rathelot, Pascal; Crozet, Michel P.; Vanelle, Patrice Heterocycles, 2002 , vol. 57, # 8 p. 1423 - 1432

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.3017
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-(Chloromethyl)-1H-benzo[d]imidazole sigma2-(Chloromethyl)-1H-benzo[d]imidazole manufacturer2-(Chloromethyl)-1H-benzo[d]imidazole price2-(Chloromethyl)-1H-benzo[d]imidazole structure2-(Chloromethyl)-1H-benzo[d]imidazole SDSbuy 2-(Chloromethyl)-1H-benzo[d]imidazole2-(Chloromethyl)-1H-benzo[d]imidazole supplier2-(Chloromethyl)-1H-benzo[d]imidazole uses2-(Chloromethyl)-1H-benzo[d]imidazole molecular weightprice of 2-(Chloromethyl)-1H-benzo[d]imidazole2-(Chloromethyl)-1H-benzo[d]imidazole chemical name formula of 2-(Chloromethyl)-1H-benzo[d]imidazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label