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Structure of 485-65-4
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Hydrocinchonine is a stereodefined quinoline alkaloid featuring a reduced quinuclidine core, delivering enhanced solubility and stability compared to parent cinchona derivatives. This bench-stable scaffold integrates readily into asymmetric catalysis workflows, offering high enantioselectivity in hydrogenation reactions through its well-defined chiral environment and coordinated nitrogen centers.
Hydrocinchonine serves as a chiral auxiliary and catalyst in asymmetric synthesis, enabling enantioselective transformations through well-documented coordination with transition metals. Its rigid quinoline scaffold provides excellent stereocontrol in reductive amination and conjugate addition reactions. The molecule exhibits robust bench stability, facilitates straightforward purification, and demonstrates broad functional group tolerance, making it a reliable choice for iterative synthetic sequences in medicinal chemistry and natural product synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: