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Structure of 4793-24-2
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This sulfamoyl-substituted benzoic acid features a strategically positioned chloro and fluoro group, enabling enhanced electronic modulation and metabolic stability. The sulfamoyl moiety imparts high polarity and hydrogen-bonding capacity, facilitating solubility in aqueous systems. Designed for use in medicinal chemistry lead optimization, this compound serves as a key scaffold for targeted kinase inhibitors and bioactive heterocycles under standard bench conditions.
2-Chloro-4-fluoro-5-sulfamoylbenzoic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its ortho-halogenated benzoic acid scaffold enables palladium-catalyzed cross-coupling reactions, while the sulfamoyl group provides strong hydrogen-bonding capacity and metabolic stability. The molecule exhibits excellent bench stability and facilitates purification via crystallization, making it well-suited for scalable synthesis of kinase inhibitors and other targeted therapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: