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CS-W001157 4
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(1H-indazol-5-yl)methanol

  • CAS No. 478828-52-3

  • Cat. No. CS-W020723
  • Purity≥98%
  • MDL No.MFCD04038636

*For research and further manufacturing use only, not for direct human use.

(1H-indazol-5-yl)methanol|CS-W020723

Structure of 478828-52-3

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General Information

  • CAS No. 478828-52-3
  • Cat. No. CS-W020723
  • Purity ≥98%
  • MDL No. MFCD04038636
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂O
  • Molecular Weight 148.16
  • Synonym(s) 1H-Indazole-5-methanol
  • SMILES OCC1=CC2=C(NN=C2)C=C1

Description

This bench-stable (1H-indazol-5-yl)methanol features a polar hydroxymethyl group appended to an electron-deficient indazole core, enabling straightforward functionalization. The scaffold integrates readily into bioactive molecule design and serves as a direct precursor for C–H oxidation or coupling reactions under standard conditions.

Application

(1H-indazol-5-yl)methanol serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient functionalization at the indazole core. Its benzylic alcohol functionality facilitates oxidation to the aldehyde or carboxylic acid, and it participates reliably in coupling reactions such as Mitsunobu and Suzuki-Miyaura protocols. The molecule exhibits good bench stability, ease of purification, and compatibility with diverse functional groups, making it well-suited for scalable synthesis of bioactive scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   1.0552
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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