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Structure of 478375-37-0
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Methyl 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a bench-stable boronate ester featuring a methyl ester and methoxy group positioned ortho and para to the boronate moiety. This electronic and steric configuration enables efficient coupling in Suzuki-Miyaura reactions, facilitating rapid access to functionalized biaryl scaffolds under mild conditions.
Methyl 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The pinacol boronate group enables stable, air-tolerant handling and broad functional group compatibility. It facilitates efficient C–C bond formation with aryl, heteroaryl, and vinyl halides under mild conditions, making it well-suited for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: