Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-2-iodo-3-methoxypyrazine

  • CAS No. 476622-89-6

  • Cat. No. CS-W000776
  • Purity≥97%
  • MDL No.MFCD09909688

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-iodo-3-methoxypyrazine|CS-W000776

Structure of 476622-89-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 476622-89-6
  • Cat. No. CS-W000776
  • Purity ≥97%
  • MDL No. MFCD09909688
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrIN₂O
  • Molecular Weight 314.91
  • Synonym(s) None
  • SMILES COC1=C(N=CC(Br)=N1)I

Description

5-Bromo-2-iodo-3-methoxypyrazine is a halogenated pyrazine derivative featuring complementary reactive sites for cross-coupling transformations. The bromo and iodo substituents enable sequential functionalization, while the methoxy group enhances solubility and modulates electronic properties. This compound serves as a strategic intermediate in the synthesis of complex heterocyclic architectures.

Application

5-Bromo-2-iodo-3-methoxypyrazine serves as a versatile dihalogenated pyrazine building block for transition-metal-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization under palladium or nickel catalysis, while the methoxy group provides moderate electron donation and enhances solubility. Its bench-stable nature and orthogonal reactivity profile facilitate efficient synthesis of complex heterocyclic scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Garg, Neil K.; Sarpong, Richmond; Stoltz, Brian M. Journal of the American Chemical Society, 2002 , vol. 124, # 44 p. 13179 - 13184

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.01
  • LogP   1.8523
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-2-iodo-3-methoxypyrazine sigma5-Bromo-2-iodo-3-methoxypyrazine manufacturer5-Bromo-2-iodo-3-methoxypyrazine price5-Bromo-2-iodo-3-methoxypyrazine structure5-Bromo-2-iodo-3-methoxypyrazine SDSbuy 5-Bromo-2-iodo-3-methoxypyrazine5-Bromo-2-iodo-3-methoxypyrazine supplier5-Bromo-2-iodo-3-methoxypyrazine uses5-Bromo-2-iodo-3-methoxypyrazine molecular weightprice of 5-Bromo-2-iodo-3-methoxypyrazine5-Bromo-2-iodo-3-methoxypyrazine chemical name formula of 5-Bromo-2-iodo-3-methoxypyrazine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label