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CS-W001157 4
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Methyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate

  • CAS No. 476168-17-9

  • Cat. No. CS-0570185
  • Molecule weight299.32
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate|CS-0570185

Structure of 476168-17-9

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General Information

  • CAS No. 476168-17-9
  • Cat. No. CS-0570185
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₁NO₆
  • Molecular Weight 299.32
  • Synonym(s) METHYL ESTER, 2-AMINO-4,5-BIS(2-METHOXYETHOXY)BENZOIC ACID
  • SMILES COCCOC1=C(C=C(C(=C1)C(=O)OC)N)OCCOC

Synthesis

  • Route1
    • Erlotinib Impurity 13|CS-1004013
      501684-22-6
    • ~99%
    • Methyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate|CS-0570185
      476168-17-9

    References

    • Nakamura, Hiroyuki; Onagi, Shinya Tetrahedron Letters, 2006 , vol. 47, # 15 p. 2539 - 2542
  • Route2
    • Methyl 3,4-bis(2-methoxyethoxy)benzoate|CS-0699571
      179688-14-3
    • ~%
    • Methyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate|CS-0570185
      476168-17-9

    References

    • Zheng, Youguang; Sun, Min; Liu, Yi; Li, Mingdong; Ji, Min Medicinal Chemistry, 2011 , vol. 7, # 4 p. 295 - 300
  • Route3
    • 3,4-Dihydroxybenzoic acid Erlotinib Impurity|CS-0167073
      99-50-3
    • ~%
    • Methyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate|CS-0570185
      476168-17-9

    References

    • Nakamura, Hiroyuki; Onagi, Shinya Tetrahedron Letters, 2006 , vol. 47, # 15 p. 2539 - 2542

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   89.24
  • LogP   1.1058
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   9

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