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CS-W001157 4
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7-Methoxyquinoline-3-carboxylic acid

  • CAS No. 474659-26-2

  • Cat. No. CS-0133768
  • Purity≥98%
  • MDL No.MFCD09787873
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Methoxyquinoline-3-carboxylic acid|CS-0133768

Structure of 474659-26-2

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Description

7-Methoxyquinoline-3-carboxylic acid features a quinoline core functionalized with a methoxy group at the 7-position and a carboxylic acid at the 3-position, offering enhanced solubility and stability. This dual-functional scaffold integrates readily into pharmaceutical intermediates and bioactive molecule design, enabling efficient coupling reactions under standard conditions.

Application

7-Methoxyquinoline-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of quinoline-based scaffolds through standard coupling reactions. Its carboxylic acid functionality facilitates amide and ester formation under mild conditions, while the 7-methoxy group enhances solubility and modulates electronic properties. The molecule exhibits bench stability and compatibility with common protecting group strategies, supporting efficient purification and integration into multi-step syntheses.

General Information

  • CAS No. 474659-26-2
  • Cat. No. CS-0133768
  • Purity ≥98%
  • MDL No. MFCD09787873
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉NO₃
  • Molecular Weight 203.19
  • Synonym(s) 7-Methoxy-3-Quinolinecarboxylic Acid
  • SMILES O=C(O)C1=CC2=CC=C(C=C2N=C1)OC

Computational Chemistry Data

  • TPSA   59.42
  • LogP   1.9416
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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