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CS-W001157 4
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2-({[(tert-Butoxy)carbonyl]amino}methyl)pyridine-4-carboxylic acid

  • CAS No. 473924-63-9

  • Cat. No. CS-0223308
  • Molecule weight252.27
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-({[(tert-Butoxy)carbonyl]amino}methyl)pyridine-4-carboxylic acid|CS-0223308

Structure of 473924-63-9

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General Information

  • CAS No. 473924-63-9
  • Cat. No. CS-0223308
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆N₂O₄
  • Molecular Weight 252.27
  • Synonym(s) 2-{[(TERT-BUTOXYCARBONYL)AMINO]METHYL}ISONICOTINIC ACID
  • SMILES CC(C)(OC(NCC1=NC=CC(C(O)=O)=C1)=O)C

Description

This pyridine-based scaffold features a tert-butoxycarbonyl-protected amine and a carboxylic acid group, enabling orthogonal functionalization. The molecule integrates seamlessly into peptide coupling workflows and serves as a key intermediate for bioactive compound synthesis under standard bench conditions.

Application

2-({[(tert-Butoxy)carbonyl]amino}methyl)pyridine-4-carboxylic acid serves as a versatile building block for pyridine-based pharmacophores, enabling efficient access to bioactive scaffolds via orthogonal deprotection. The tert-butyl carbamate (Boc) group ensures stability and compatibility with standard coupling reactions, while the carboxylic acid facilitates amide bond formation. Its dual functionality supports modular synthesis of heterocyclic compounds in medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   88.52
  • LogP   1.8045
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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