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CS-W001157 4
Total: USD 88.00

2-(1H-Benzo[d]imidazol-6-yl)acetic acid

  • CAS No. 473895-86-2

  • Cat. No. CS-W005937
  • Molecule weight176.17
  • Purity≥98%
  • MDL No.MFCD08690200

*For research and further manufacturing use only, not for direct human use.

2-(1H-Benzo[d]imidazol-6-yl)acetic acid|CS-W005937

Structure of 473895-86-2

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General Information

  • CAS No. 473895-86-2
  • Cat. No. CS-W005937
  • Purity ≥98%
  • MDL No. MFCD08690200
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂
  • Molecular Weight 176.17
  • Synonym(s) 2-(3H-Benzimidazol-5-yl)acetic acid
  • SMILES O=C(O)CC1=CC=C2C(NC=N2)=C1

Description

This benzoimidazole-acetic acid derivative integrates a rigid heterocyclic core with a flexible carboxylate handle, enabling efficient conjugation in bioconjugation workflows. The electron-rich aromatic system enhances solubility and stability under physiological conditions, while the terminal carboxylic acid facilitates direct coupling to amines or activation for amide bond formation.

Application

2-(1H-Benzo[d]imidazol-6-yl)acetic acid serves as a versatile building block for bioactive heterocycles, enabling efficient incorporation of the benzoimidazole pharmacophore into drug-like scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization, while the stable, planar aromatic system supports orthogonal functional group manipulation. Bench-stable and readily purified by recrystallization, it functions reliably in standard peptide coupling and conjugation workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.19
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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