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CS-W001157 4
Total: USD 88.00

3,5-Dichloropicolinaldehyde

  • CAS No. 471909-65-6

  • Cat. No. CS-0019192
  • Purity≥97%
  • MDL No.MFCD09839149

*For research and further manufacturing use only, not for direct human use.

3,5-Dichloropicolinaldehyde|CS-0019192

Structure of 471909-65-6

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General Information

  • CAS No. 471909-65-6
  • Cat. No. CS-0019192
  • Purity ≥97%
  • MDL No. MFCD09839149
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Cl₂NO
  • Molecular Weight 176.00
  • Synonym(s) None
  • SMILES O=CC1=NC=C(Cl)C=C1Cl

Description

3,5-Dichloropicolinaldehyde features a pyridine ring bearing two chlorine substituents at the 3 and 5 positions, creating a highly electron-deficient aldehyde. This configuration enhances reactivity in nucleophilic addition processes and enables selective functionalization in synthetic transformations. The compound exhibits stability under standard handling conditions and serves as a key building block for heterocyclic scaffolds and bioactive molecule synthesis.

Application

3,5-Dichloropicolinaldehyde serves as a versatile building block in synthetic organic chemistry, enabling the construction of heterocyclic scaffolds and functionalized aromatic systems. Its electron-deficient pyridine core facilitates nucleophilic addition and condensation reactions, while the aldehyde group provides a handle for imine formation, reductive amination, or incorporation into larger frameworks. The dichloro substitution enhances reactivity and metabolic stability in downstream applications, offering improved bench stability and ease of purification compared to less substituted analogs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.2009
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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