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CS-W001157 4
Total: USD 88.00

4-Methoxyphenylacetyl chloride

  • CAS No. 4693-91-8

  • Cat. No. CS-0124988
  • Purity≥98%
  • MDL No.MFCD00075474

*For research and further manufacturing use only, not for direct human use.

4-Methoxyphenylacetyl chloride|CS-0124988

Structure of 4693-91-8

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General Information

  • CAS No. 4693-91-8
  • Cat. No. CS-0124988
  • Purity ≥98%
  • MDL No. MFCD00075474
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉ClO₂
  • Molecular Weight 184.62
  • Synonym(s) None
  • SMILES O=C(Cl)CC1=CC=C(OC)C=C1

Description

4-Methoxyphenylacetyl chloride is a reactive acylating agent featuring a para-methoxy-substituted phenyl group that enhances solubility and stability. This reagent facilitates efficient amide bond formation under mild conditions, offering high functional group tolerance. It serves as a key intermediate in the synthesis of bioactive compounds and pharmaceuticals requiring aromatic acyl linkages.

Application

4-Methoxyphenylacetyl chloride serves as a versatile acylating agent for the introduction of the 4-methoxyphenylacetyl group into target molecules. It facilitates efficient amide and ester formation under mild conditions, exhibits good bench stability, and enables straightforward purification due to its low tendency for hydrolysis during standard handling. This reagent is particularly valuable in medicinal chemistry for constructing bioactive scaffolds and peptide derivatives requiring ortho- or para-substituted aryl acyl linkages.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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