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CS-W001157 4
Total: USD 88.00

2-Bromo-5-formylthiazole

  • CAS No. 464192-28-7

  • Cat. No. CS-W019735
  • Purity≥95%
  • MDL No.MFCD03788567

*For research and further manufacturing use only, not for direct human use.

2-Bromo-5-formylthiazole|CS-W019735

Structure of 464192-28-7

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General Information

  • CAS No. 464192-28-7
  • Cat. No. CS-W019735
  • Purity ≥95%
  • MDL No. MFCD03788567
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂BrNOS
  • Molecular Weight 192.03
  • Synonym(s) 2-Bromothiazole-5-carboxaldehyde
  • SMILES O=CC1=CN=C(Br)S1

Application

2-Bromo-5-formylthiazole serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions at the bromine site while retaining the formyl group for further functionalization. Its stability under standard handling conditions and compatibility with diverse reaction partners make it a practical reagent for constructing complex thiazole-based scaffolds relevant to medicinal chemistry and agrochemical development.

Synthesis

  • Route1

    References

    • WO2008/61795 A2, ; Page/Page column 61-62 ; WO 2008/061795 A2
  • Route2

    References

    • WO2004/37818 A1, ; Page 69 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H319
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.7181
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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