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CS-W001157 4
Total: USD 88.00

2-(2-Methoxypyridin-4-yl)acetic acid

  • CAS No. 464152-38-3

  • Cat. No. CS-W006502
  • Molecule weight167.16
  • Purity≥95%
  • MDL No.MFCD10698166

*For research and further manufacturing use only, not for direct human use.

2-(2-Methoxypyridin-4-yl)acetic acid|CS-W006502

Structure of 464152-38-3

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General Information

  • CAS No. 464152-38-3
  • Cat. No. CS-W006502
  • Purity ≥95%
  • MDL No. MFCD10698166
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) 4-Pyridineaceticacid,2-methoxy-(9CI)
  • SMILES COC1=NC=CC(CC(O)=O)=C1

Description

This acetic acid derivative features a methoxypyridine moiety that enhances solubility and metabolic stability. It serves as a key scaffold in bioactive molecule design, particularly in kinase inhibitors and pharmaceutical intermediates. The para-methoxy group provides electron-donating character, while the carboxylic acid enables facile derivatization.

Application

2-(2-Methoxypyridin-4-yl)acetic acid serves as a versatile building block for constructing bioactive heterocycles and pharmaceutical intermediates. Its pyridine core enables metal-catalyzed cross-coupling, while the carboxylic acid group facilitates amide bond formation and derivatization. The methoxy substituent enhances solubility and modulates electronic properties, contributing to improved stability and ease of purification in synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.7173
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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