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CS-W001157 4
Total: USD 88.00

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Dapagliflozin Impurity

  • CAS No. 461432-23-5

  • Cat. No. CS-0214035
  • Purity≥97%
  • MDL No.MFCD11042292

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Dapagliflozin Impurity|CS-0214035

Structure of 461432-23-5

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General Information

  • CAS No. 461432-23-5
  • Cat. No. CS-0214035
  • Purity ≥97%
  • MDL No. MFCD11042292
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₄BrClO
  • Molecular Weight 325.63
  • Synonym(s) None
  • SMILES CCOC1=CC=C(CC2=CC(Br)=CC=C2Cl)C=C1

Synthesis

  • Route1
    • (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone  Dapagliflozin Impurity|CS-0167411
      461432-22-4
    • ~95%
    • 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Dapagliflozin Impurity|CS-0214035
      461432-23-5

    References

    • WO2010/22313 A2, ; Page/Page column 35-37 ; WO 2010/022313 A2
  • Route2
    • (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone  Dapagliflozin Impurity|CS-0167411
      461432-22-4
    • null|null
      107-06-2
    • ~%
    • 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Dapagliflozin Impurity|CS-0214035
      461432-23-5

    References

    • US2002/137903 A1, ; US 20020137903 A1 US6515117 B2, ;
  • Route3

    References

    • Bioorganic and Medicinal Chemistry, , vol. 21, # 21 p. 6282 - 6291

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   5.092
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   4

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