Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Chloro-4-(trifluoromethoxy)benzene

  • CAS No. 461-81-4

  • Cat. No. CS-W010583
  • Purity≥98%
  • MDL No.MFCD00040953

*For research and further manufacturing use only, not for direct human use.

1-Chloro-4-(trifluoromethoxy)benzene|CS-W010583

Structure of 461-81-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 461-81-4
  • Cat. No. CS-W010583
  • Purity ≥98%
  • MDL No. MFCD00040953
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClF₃O
  • Molecular Weight 196.55
  • Synonym(s) 4-Chloro(trifluoromethoxy)benzene
  • SMILES FC(F)(F)OC1=CC=C(Cl)C=C1

Description

1-Chloro-4-(trifluoromethoxy)benzene features a trifluoromethoxy group that imparts enhanced electron-withdrawal and metabolic stability, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. The chlorine atom serves as a robust electrophilic handle for C–C bond formation under standard conditions.

Synthesis

  • Route1
    • null|null
      56-23-5
    • null|null
      106-48-9
    • ~63%
    • In-stock
      1-Chloro-4-(trifluoromethoxy)benzene|CS-W010583
      461-81-4

    References

    • Olah,G.A.; Yamato,T.; Hashimoto,T. Journal of the American Chemical Society, 1987 , vol. 109, p. 3708
  • Route2
    • null|null
      373-91-1
    • null|null
      108-90-7
    • ~%
    • null|null
      348-51-6
    • null|null
      352-33-0
    • In-stock
      1-Chloro-2-(trifluoromethoxy)benzene|CS-W003122
      450-96-4
    • null|null
      625-98-9
    • In-stock
      1-Chloro-4-(trifluoromethoxy)benzene|CS-W010583
      461-81-4
    • In-stock
      1-Chloro-3-(trifluoromethoxy)benzene|CS-W015693
      772-49-6

    References

    • Venturini, Francesco; Navarrini, Walter; Famulari, Antonino; Sansotera, Maurizio; Dardani, Patrizia; Tortelli, Vito Journal of Fluorine Chemistry, 2012 , vol. 140, p. 43 - 48
  • Route3

    References

    • Olah,G.A.; Yamato,T.; Hashimoto,T. Journal of the American Chemical Society, 1987 , vol. 109, p. 3708

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.2386
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Chloro-4-(trifluoromethoxy)benzene sigma1-Chloro-4-(trifluoromethoxy)benzene manufacturer1-Chloro-4-(trifluoromethoxy)benzene price1-Chloro-4-(trifluoromethoxy)benzene structure1-Chloro-4-(trifluoromethoxy)benzene SDSbuy 1-Chloro-4-(trifluoromethoxy)benzene1-Chloro-4-(trifluoromethoxy)benzene supplier1-Chloro-4-(trifluoromethoxy)benzene uses1-Chloro-4-(trifluoromethoxy)benzene molecular weightprice of 1-Chloro-4-(trifluoromethoxy)benzene1-Chloro-4-(trifluoromethoxy)benzene chemical name formula of 1-Chloro-4-(trifluoromethoxy)benzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label