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CS-W001157 4
Total: USD 88.00

5-Bromo-3-iodoindazole

  • CAS No. 459133-66-5

  • Cat. No. CS-M1446
  • Purity≥98%
  • MDL No.MFCD07781637
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-iodoindazole|CS-M1446

Structure of 459133-66-5

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Description

5-Bromo-3-iodoindazole is a halogenated indazole scaffold featuring complementary reactive sites at the 5-bromo and 3-iodo positions. This dual-halogenation enables efficient cross-coupling transformations, particularly in palladium-catalyzed reactions, facilitating rapid access to complex heterocyclic architectures. The molecule exhibits high stability under standard conditions and serves as a key intermediate in medicinal chemistry and materials science applications.

Application

5-Bromo-3-iodoindazole serves as a versatile biaryl building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of complex indazole-based scaffolds. The orthogonal halogen reactivity facilitates sequential functionalization, while the compound exhibits excellent bench stability and compatibility with standard Pd(0)-catalyzed coupling protocols. Its defined substitution pattern supports precise molecular design in medicinal chemistry and materials science applications.

General Information

  • CAS No. 459133-66-5
  • Cat. No. CS-M1446
  • Purity ≥98%
  • MDL No. MFCD07781637
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrIN₂
  • Molecular Weight 322.93
  • Synonym(s) 5-Bromo-3-iodo-1H-indazole
  • SMILES BrC1=CC2=C(NN=C2I)C=C1

Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.93
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group :
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P264-P270-P330-P405-P501

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