(R)-1-Methylpyrrolidin-3-amine

Name: (R)-1-Methylpyrrolidin-3-amine
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CAS No. 457097-75-5
Cat. No. CS-0053339
Purity≥97%
MDL No.None

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-1-Methylpyrrolidin-3-amine|CS-0053339

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General Information

CAS No. 457097-75-5
Cat. No. CS-0053339
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₂N₂
Molecular Weight 100.16
Synonym(s) (3R)-1-methylpyrrolidin-3-amine
SMILES CN1CC[C@@H](N)C1

Description

(R)-1-Methylpyrrolidin-3-amine is a chiral amine featuring a stereodefined pyrrolidine core with enhanced solubility and stability. This bench-stable, moisture-tolerant scaffold integrates readily into asymmetric synthesis, serving as a key building block in medicinal chemistry for targeted ligand design and catalyst development.

Application

(R)-1-Methylpyrrolidin-3-amine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of diverse nitrogen-containing scaffolds. Its well-defined stereochemistry and amine functionality facilitate efficient coupling reactions and incorporation into bioactive molecules. The compound exhibits good bench stability and compatibility with common functional groups, making it suitable for multi-step syntheses and process-scale applications.

Safety Information

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GHS Pictogram :	GHS No : GHS02,GHS05
Signal Word : Danger	UN#: 2735
Class : 8	Packing Group : Ⅲ
Hazard Statements : H225-H314
Precautionary Statements : P210-P240-P241-P280-P370+P378

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Computational Chemistry Data

TPSA 29.26
LogP -0.3508
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Key Words

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(R)-1-Methylpyrrolidin-3-amine

CAS No. 457097-75-5

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