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CS-W001157 4
Total: USD 88.00

2-Amino-1-(4-fluorophenyl)ethan-1-ol

  • CAS No. 456-05-3

  • Cat. No. CS-0452649
  • Molecule weight155.17
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Amino-1-(4-fluorophenyl)ethan-1-ol|CS-0452649

Structure of 456-05-3

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General Information

  • CAS No. 456-05-3
  • Cat. No. CS-0452649
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀FNO
  • Molecular Weight 155.17
  • Synonym(s) Benzenemethanol, a-(aminomethyl)-4-fluoro-
  • SMILES C1=C(C=CC(=C1)F)C(CN)O

Synthesis

  • Route1
    • 2-(4-Fluorophenyl)oxirane|CS-0063809
      18511-62-1
    • ~79%
    • 2-Amino-1-(4-fluorophenyl)ethan-1-ol|CS-0452649
      456-05-3

    References

    • Murugan, Andiappan; Kadambar, Vasantha Krishna; Bachu, Sreekanth; Rajashekher Reddy; Torlikonda, Venkatarao; Manjunatha, Sulur G.; Ramasubramanian, Sridharan; Nambiar, Sudhir; Howell, Gareth P.; Withnall, Jane Tetrahedron Letters, 2012 , vol. 53, # 43 p. 5739 - 5741
  • Route2
    • null|null
      1029598-42-2
    • ~%
    • 2-Amino-1-(4-fluorophenyl)ethan-1-ol|CS-0452649
      456-05-3

    References

    • Liu, Feng; Li, Fengling; Ma, Anqi; Dobrovetsky, Elena; Dong, Aiping; Gao, Cen; Korboukh, Ilia; Liu, Jing; Smil, David; Brown, Peter J.; Frye, Stephen V.; Arrowsmith, Cheryl H.; Schapira, Matthieu; Vedadi, Masoud; Jin, Jian Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 2110 - 2124
  • Route3
    • Tert-butyl (2-(4-fluorophenyl)-2-hydroxyethyl)carbamate|CS-0456495
      864539-93-5
    • ~%
    • 2-Amino-1-(4-fluorophenyl)ethan-1-ol|CS-0452649
      456-05-3

    References

    • H. LUNDBECK A/S Patent: WO2005/87754 A1, 2005 ; Location in patent: Page/Page column 43-44 ; WO 2005/087754 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302+H312+H332-H314
Precautionary Statements : P260-P271-P280

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.8178
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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