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CS-W001157 4
Total: USD 88.00

4-Amino-3-fluorobenzoic acid

  • CAS No. 455-87-8

  • Cat. No. CS-W008331
  • Purity≥95%
  • MDL No.MFCD01660374

*For research and further manufacturing use only, not for direct human use.

4-Amino-3-fluorobenzoic acid|CS-W008331

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General Information

  • CAS No. 455-87-8
  • Cat. No. CS-W008331
  • Purity ≥95%
  • MDL No. MFCD01660374
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆FNO₂
  • Molecular Weight 155.13
  • Synonym(s) None
  • SMILES C1=CC(=C(C=C1C(O)=O)F)N

Description

4-Amino-3-fluorobenzoic acid features a strategically positioned amino group flanked by fluorine and carboxylic acid functionalities, enabling precise tuning of electronic properties and solubility. This combination facilitates direct incorporation into bioactive scaffolds and peptide conjugates under standard conditions.

Application

4-Amino-3-fluorobenzoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling direct incorporation of electron-withdrawing fluorine and amino functionalities into heterocyclic scaffolds. Its dual polar groups facilitate efficient derivatization via amide coupling, diazotization, or electrophilic substitution, while the carboxylic acid supports straightforward salt formation and purification. Bench-stable and compatible with standard reaction conditions, it functions reliably in multi-step syntheses requiring precise regiocontrol and functional group tolerance.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.1061
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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