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CS-W001157 4
Total: USD 88.00

4-Fluoro-2-methylphenol

  • CAS No. 452-72-2

  • Cat. No. CS-W013499
  • Purity≥98%
  • MDL No.MFCD00075088

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-2-methylphenol|CS-W013499

Structure of 452-72-2

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General Information

  • CAS No. 452-72-2
  • Cat. No. CS-W013499
  • Purity ≥98%
  • MDL No. MFCD00075088
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇FO
  • Molecular Weight 126.13
  • Synonym(s) 2-METHYL-4-FLUOROPHENOL
  • SMILES C1=C(C(=CC=C1F)O)C

Description

4-Fluoro-2-methylphenol features a fluorine atom at the para position and a methyl group at the ortho position relative to the hydroxyl group, creating a uniquely activated aromatic system. This configuration enhances electrophilic substitution reactivity while maintaining bench-stable handling characteristics. The molecule integrates readily into synthetic pathways requiring electron-deficient phenolic scaffolds.

Synthesis

  • Route1
    • null|null
      1338215-44-3
    • ~80%
    • In-stock
      4-Fluoro-2-methylphenol|CS-W013499
      452-72-2

    References

    • Dibakar, Mullick; Prakash, Anjanappa; Selvakumar, Kumaravel; Ruckmani, Kandasamy; Sivakumar, Manickam Tetrahedron Letters, 2011 , vol. 52, # 41 p. 5338 - 5341
  • Route2

    References

    • Samant, Bhupesh S.; Bhagwat, Sunil S. Applied Catalysis A: General, 2011 , vol. 394, # 1-2 p. 191 - 194
  • Route3
    • null|null
      352-70-5
    • ~%
    • In-stock
      4-Fluoro-2-methylphenol|CS-W013499
      452-72-2

    References

    • Nakano, Taku; Kawabata, Sally; Sugihara, Tamami; Agatsuma, Noriko; Kakuda, Hiroko; Mori, Yoshihiro Bulletin of the Chemical Society of Japan, 2003 , vol. 76, # 12 p. 2353 - 2360

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.83972
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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