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CS-W001157 4
Total: USD 88.00

H-D-Glu(OtBu)-OH

  • CAS No. 45125-00-6

  • Cat. No. CS-W015459
  • Purity≥97%
  • MDL No.MFCD00153437

*For research and further manufacturing use only, not for direct human use.

H-D-Glu(OtBu)-OH|CS-W015459

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General Information

  • CAS No. 45125-00-6
  • Cat. No. CS-W015459
  • Purity ≥97%
  • MDL No. MFCD00153437
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₄
  • Molecular Weight 203.24
  • Synonym(s) D-GLUTAMIC ACID-Y-T-BUTYLESTER
  • SMILES O=C(O)[C@H](N)CCC(OC(C)(C)C)=O

Description

H-D-Glu(OtBu)-OH is a protected D-glutamic acid derivative featuring a tert-butyl ester group, enabling stable incorporation into peptide syntheses. This configuration supports efficient coupling under standard conditions while offering enhanced solubility and handling advantages in solution-phase and solid-phase workflows.

Application

H-D-Glu(OtBu)-OH serves as a stable, bench-ready building block for the synthesis of peptide-based scaffolds and bioactive molecules. The tert-butyl ester group provides excellent functional group tolerance and simplifies purification, while the D-glutamic acid backbone enables incorporation into cyclic peptides and constrained peptidomimetics. This derivative facilitates efficient coupling reactions and is well-suited for solid-phase and solution-phase synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   89.62
  • LogP   0.5202
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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