1-Bromo-3-chloro-2-iodobenzene

Name: 1-Bromo-3-chloro-2-iodobenzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 450412-28-9
Cat. No. CS-0097777
Purity≥96%
MDL No.MFCD09907935

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Bromo-3-chloro-2-iodobenzene|CS-0097777

Structure of 450412-28-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 450412-28-9
Cat. No. CS-0097777
Purity ≥96%
MDL No. MFCD09907935
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃BrClI
Molecular Weight 317.35
Synonym(s) 1-Bromo-3-chloro-2-Iodobenzenne
SMILES IC1=C(Cl)C=CC=C1Br

Description

1-Bromo-3-chloro-2-iodobenzene is a trihalogenated aromatic compound featuring distinct halogen substituents at adjacent positions on the benzene ring. This configuration enables selective cross-coupling reactions in transition-metal-catalyzed processes, offering predictable regiochemical outcomes. The molecule combines moderate stability with high reactivity, making it valuable for constructing complex heterocycles and functionalized biaryls under standard conditions.

Application

1-Bromo-3-chloro-2-iodobenzene serves as a versatile trihalogenated benzene building block for palladium-catalyzed cross-coupling reactions. Its orthogonal halogen reactivity enables sequential functionalization, facilitating the construction of complex biaryl and heterocyclic scaffolds. The compound exhibits good bench stability and is compatible with standard coupling conditions, offering predictable regioselectivity in iterative synthesis workflows.

Synthesis

Route1
- In-stock
  
  108-37-2
- ~88%
- In-stock
  
  450412-28-9
References
- SMITHKLINE BEECHAM CORPORATION; VITAE PHARMACEUTICALS, INC. Patent: WO2008/124575 A1, 2008 ; Location in patent: Page/Page column 103 ; WO 2008/124575 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 0
LogP 3.7071
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1-Bromo-3-chloro-2-iodobenzene sigma1-Bromo-3-chloro-2-iodobenzene manufacturer1-Bromo-3-chloro-2-iodobenzene price1-Bromo-3-chloro-2-iodobenzene structure1-Bromo-3-chloro-2-iodobenzene SDSbuy 1-Bromo-3-chloro-2-iodobenzene1-Bromo-3-chloro-2-iodobenzene supplier1-Bromo-3-chloro-2-iodobenzene uses1-Bromo-3-chloro-2-iodobenzene molecular weightprice of 1-Bromo-3-chloro-2-iodobenzene1-Bromo-3-chloro-2-iodobenzene chemical name formula of 1-Bromo-3-chloro-2-iodobenzene

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-Bromo-3-chloro-2-iodobenzene

CAS No. 450412-28-9

Recommended Products