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CS-W001157 4
Total: USD 88.00

6,11-Dihydro-5H-dibenzo[b,e]azepine

  • CAS No. 449-55-8

  • Cat. No. CS-0112646
  • Molecule weight195.26
  • Purity95+%
  • MDL No.MFCD03723999

*For research and further manufacturing use only, not for direct human use.

6,11-Dihydro-5H-dibenzo[b,e]azepine|CS-0112646

Structure of 449-55-8

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General Information

  • CAS No. 449-55-8
  • Cat. No. CS-0112646
  • Purity 95+%
  • MDL No. MFCD03723999
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₃N
  • Molecular Weight 195.26
  • Synonym(s) 6,11-dihydro-5H-dibenz[b,e]azepine
  • SMILES C12=CC=CC=C1CC3=CC=CC=C3CN2

Synthesis

  • Route1
    • 9-Azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,11,13-hexaen-10-one|CS-0257489
      1211-06-9
    • ~80%
    • 6,11-Dihydro-5H-dibenzo[b,e]azepine|CS-0112646
      449-55-8

    References

    • ACTELION PHARMACEUTICALS LTD Patent: WO2005/94816 A1, 2005 ; Location in patent: Page/Page column 70 ; WO 2005/094816 A1
  • Route2
    • Morphanthridine|CS-1673101
      256-86-0
    • ~93%
    • 6,11-Dihydro-5H-dibenzo[b,e]azepine|CS-0112646
      449-55-8

    References

    • Andres; Alcazar, Jesus; Alonso, Jose M.; Diaz, Adolfo; Fernandez, Javier; Gil, Pilar; Iturrino, Laura; Matesanz, Encarna; Meert, Theo F.; Megens, Anton; Sipido, Victor K. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 243 - 248
  • Route3
    • (2-(Benzylamino)phenyl)methanol|CS-0336866
      1722-07-2
    • ~85%
    • 6,11-Dihydro-5H-dibenzo[b,e]azepine|CS-0112646
      449-55-8

    References

    • Andres; Alcazar, Jesus; Alonso, Jose M.; Diaz, Adolfo; Fernandez, Javier; Gil, Pilar; Iturrino, Laura; Matesanz, Encarna; Meert, Theo F.; Megens, Anton; Sipido, Victor K. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 243 - 248

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   3.2029
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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