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CS-W001157 4
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Potassium cyclohexyltrifluoroborate

  • CAS No. 446065-11-8

  • Cat. No. CS-0155342
  • Purity≥98%
  • MDL No.MFCD09992929

*For research and further manufacturing use only, not for direct human use.

Potassium cyclohexyltrifluoroborate|CS-0155342

Structure of 446065-11-8

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General Information

  • CAS No. 446065-11-8
  • Cat. No. CS-0155342
  • Purity ≥98%
  • MDL No. MFCD09992929
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁BF₃K
  • Molecular Weight 190.06
  • Synonym(s) potassium cyclohexyltrifluoroboranuide
  • SMILES C1CCC(CC1)[B-](F)(F)F.[K+]

Description

Potassium cyclohexyltrifluoroborate offers a bench-stable, moisture-tolerant boron source for Suzuki-Miyaura cross-coupling reactions. This reagent integrates seamlessly into synthetic workflows, delivering reliable C–C bond formation under mild conditions. The cyclohexyl group provides steric bulk that enhances selectivity and minimizes protodeboronation.

Application

Potassium cyclohexyltrifluoroborate serves as a stable, bench-friendly boron source for Suzuki-Miyaura cross-coupling reactions. It exhibits excellent functional group tolerance and enables efficient C–C bond formation with aryl and vinyl halides under mild conditions. The reagent's crystalline nature facilitates handling and purification, making it well-suited for scalable synthesis of cyclohexyl-substituted aromatic and heteroaromatic scaffolds.

Synthesis

  • Route1
    • null|null
      110-83-8
    • ~84%
    • In-stock
      Potassium cyclohexyltrifluoroborate|CS-0155342
      446065-11-8

    References

    • Clay, Julia M.; Vedejs, Edwin Journal of the American Chemical Society, 2005 , vol. 127, # 16 p. 5766 - 5767
  • Route2
    • null|null
      931-51-1
    • ~64%
    • In-stock
      Potassium cyclohexyltrifluoroborate|CS-0155342
      446065-11-8

    References

    • Dreher, Spencer D.; Dormer, Peter G.; Sandrock, Deidre L.; Molander, Gary A. Journal of the American Chemical Society, 2008 , vol. 130, # 29 p. 9257 - 9259
  • Route3
    • null|null
      931-50-0
    • ~%
    • In-stock
      Potassium cyclohexyltrifluoroborate|CS-0155342
      446065-11-8

    References

    • Vieira, Adriano S.; Ferreira, Fernando P.; Guarezemini, Alexandre S.; Stefani, Helio A. Australian Journal of Chemistry, 2009 , vol. 62, # 8 p. 909 - 916

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   0.1721
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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