Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Fluoro-6-methoxyaniline

  • CAS No. 446-61-7

  • Cat. No. CS-W005604
  • Purity≥98%
  • MDL No.MFCD03788538

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-6-methoxyaniline|CS-W005604

Structure of 446-61-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 446-61-7
  • Cat. No. CS-W005604
  • Purity ≥98%
  • MDL No. MFCD03788538
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈FNO
  • Molecular Weight 141.14
  • Synonym(s) o-Anisidine,6-fluoro- (8CI)
  • SMILES NC1=C(OC)C=CC=C1F

Description

2-Fluoro-6-methoxyaniline features a fluorine atom at the ortho position and a methoxy group at the para position relative to the amine, creating a uniquely electron-rich aromatic scaffold. This combination imparts enhanced solubility in polar solvents and improved stability under standard bench conditions. The molecule integrates readily into pharmaceutical intermediates and functional materials via coupling reactions.

Application

2-Fluoro-6-methoxyaniline serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocycles and bioactive scaffolds. Its ortho-fluoro and para-methoxy substituents provide enhanced metabolic stability and modulated electronic properties, while the primary amine facilitates straightforward derivatization via acylation, alkylation, or coupling reactions. Bench-stable and readily purified by crystallization, it functions effectively in standard amine-based transformations.

Synthesis

  • Route1

    References

    • Kimura; Watanabe; Matsui; Hayashi; Tanaka; Ohtsuka; Saeki; Kogushi; Kabayashi; Akasaka; Yamagishi; Saitou; Yamatsu Journal of Medicinal Chemistry, 1993 , vol. 36, # 11 p. 1641 - 1653
  • Route2

    References

    • Kimura; Watanabe; Matsui; Hayashi; Tanaka; Ohtsuka; Saeki; Kogushi; Kabayashi; Akasaka; Yamagishi; Saitou; Yamatsu Journal of Medicinal Chemistry, 1993 , vol. 36, # 11 p. 1641 - 1653
  • Route3

    References

    • Kimura; Watanabe; Matsui; Hayashi; Tanaka; Ohtsuka; Saeki; Kogushi; Kabayashi; Akasaka; Yamagishi; Saitou; Yamatsu Journal of Medicinal Chemistry, 1993 , vol. 36, # 11 p. 1641 - 1653

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.4165
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Fluoro-6-methoxyaniline sigma2-Fluoro-6-methoxyaniline manufacturer2-Fluoro-6-methoxyaniline price2-Fluoro-6-methoxyaniline structure2-Fluoro-6-methoxyaniline SDSbuy 2-Fluoro-6-methoxyaniline2-Fluoro-6-methoxyaniline supplier2-Fluoro-6-methoxyaniline uses2-Fluoro-6-methoxyaniline molecular weightprice of 2-Fluoro-6-methoxyaniline2-Fluoro-6-methoxyaniline chemical name formula of 2-Fluoro-6-methoxyaniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label