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Structure of 445305-93-1
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Cyclopropylmethanesulfonamide delivers a sterically constrained sulfonamide handle ideal for bioisosteric replacement in medicinal chemistry. This bench-stable, moisture-tolerant scaffold integrates readily into target molecules, offering enhanced metabolic stability and favorable physicochemical properties in lead optimization campaigns.
Cyclopropylmethanesulfonamide serves as a stable, bench-ready sulfonamide building block for medicinal chemistry and process development. Its cyclopropylmethyl group imparts favorable steric and electronic properties, enabling efficient incorporation into bioactive molecules. The sulfonamide moiety exhibits robust functional group tolerance and facilitates hydrogen bonding in target binding interactions. This compound functions effectively in amide coupling reactions and supports the construction of diverse heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: