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CS-W001157 4
Total: USD 88.00

(S,S)-BniPr-Sabox

  • CAS No. 444575-98-8

  • Cat. No. CS-0087542
  • Purity≥97%
  • MDL No.MFCD07368373

*For research and further manufacturing use only, not for direct human use.

(S,S)-BniPr-Sabox|CS-0087542

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General Information

  • CAS No. 444575-98-8
  • Cat. No. CS-0087542
  • Purity ≥97%
  • MDL No. MFCD07368373
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₇H₃₄N₂O₂
  • Molecular Weight 418.57
  • Synonym(s) (4S,4'S)-2,2'-[2-Phenyl-1-(phenylmethyl)ethylidene]bis[4-(1-methylethyl)-4,5-dihydrooxazole]
  • SMILES CC(C)[C@H]1COC(C(CC2=CC=CC=C2)(C3=N[C@@H](C(C)C)CO3)CC4=CC=CC=C4)=N1

Description

(S,S)-BniPr-Sabox delivers a chiral, bench-stable scaffold for asymmetric synthesis, featuring a sterically hindered bis(alkyl)boronate moiety that enables efficient coupling under mild conditions. This configuration enhances stereocontrol in cross-coupling reactions, streamlining access to enantioenriched building blocks.

Application

(S,S)-BniPr-Sabox serves as a robust chiral ligand in asymmetric catalysis, enabling high enantioselectivity in transition-metal-catalyzed transformations. Its bis(oxazoline) architecture with bulky isopropyl substituents provides excellent steric control and bench stability, facilitating efficient synthesis of enantiomerically enriched intermediates. The ligand exhibits broad functional group tolerance and compatibility with common catalysts, making it a practical choice for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   5.3648
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   8

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