Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Bromo-2-nitropyridin-3-ol

  • CAS No. 443956-08-9

  • Cat. No. CS-W006076
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-2-nitropyridin-3-ol|CS-W006076

Structure of 443956-08-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 443956-08-9
  • Cat. No. CS-W006076
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrN₂O₃
  • Molecular Weight 218.99
  • Synonym(s) 6-Bromo-2-nitro-pyridin-3-ol
  • SMILES OC1=CC=C(Br)N=C1[N+]([O-])=O

Description

6-Bromo-2-nitropyridin-3-ol features a bromine substituent at the 6-position and a nitro group at the 2-position on a pyridin-3-ol scaffold. This electron-deficient heterocycle integrates readily into cross-coupling reactions, leveraging its dual functional handles for further derivatization. The phenolic hydroxyl enhances solubility and provides a site for direct functionalization or metal coordination.

Application

6-Bromo-2-nitropyridin-3-ol serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its bromo group and nitro functionality. The phenolic hydroxyl group provides additional reactivity for derivatization, while the molecule exhibits good bench stability and compatibility with standard purification methods. It functions as a key intermediate in the construction of functionalized pyridine scaffolds relevant to medicinal chemistry and agrochemical research.

Synthesis

  • Route1

    References

    • WO2006/81178 A2, ; Page/Page column 22 ;
  • Route2

    References

    • Tetrahedron Letters, , vol. 51, # 38 p. 5035 - 5037

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   76.26
  • LogP   1.4579
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Bromo-2-nitropyridin-3-ol sigma6-Bromo-2-nitropyridin-3-ol manufacturer6-Bromo-2-nitropyridin-3-ol price6-Bromo-2-nitropyridin-3-ol structure6-Bromo-2-nitropyridin-3-ol SDSbuy 6-Bromo-2-nitropyridin-3-ol6-Bromo-2-nitropyridin-3-ol supplier6-Bromo-2-nitropyridin-3-ol uses6-Bromo-2-nitropyridin-3-ol molecular weightprice of 6-Bromo-2-nitropyridin-3-ol6-Bromo-2-nitropyridin-3-ol chemical name formula of 6-Bromo-2-nitropyridin-3-ol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label