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CS-W001157 4
Total: USD 88.00

(4-(Methylsulfonyl)phenyl)methanamine

  • CAS No. 4393-16-2

  • Cat. No. CS-0079866
  • Purity≥97%
  • MDL No.MFCD06213173

*For research and further manufacturing use only, not for direct human use.

(4-(Methylsulfonyl)phenyl)methanamine|CS-0079866

Structure of 4393-16-2

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General Information

  • CAS No. 4393-16-2
  • Cat. No. CS-0079866
  • Purity ≥97%
  • MDL No. MFCD06213173
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO₂S
  • Molecular Weight 185.24
  • Synonym(s) 4-(Methylsulfonyl)benzylamine HCl
  • SMILES NCC1=CC=C(S(=O)(C)=O)C=C1

Description

This bench-stable arylamine features a methylsulfonyl group that enhances solubility and metabolic stability. The para-substituted aniline scaffold enables direct incorporation into pharmaceutical intermediates, offering improved handling and compatibility in multistep synthesis workflows.

Application

(4-(Methylsulfonyl)phenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of sulfonamide-containing pharmaceutical intermediates. Its methylsulfonyl group provides enhanced solubility and metabolic stability, while the primary amine facilitates standard coupling reactions. The compound exhibits excellent bench stability and compatibility with diverse functional groups, making it well-suited for multi-step synthetic sequences and API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   60.16
  • LogP   0.5488
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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