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CS-W001157 4
Total: USD 88.00

6-Bromobenzofuran-2-carboxylic acid

  • CAS No. 439107-94-5

  • Cat. No. CS-0005588
  • Purity≥97%
  • MDL No.MFCD03012913
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromobenzofuran-2-carboxylic acid|CS-0005588

Structure of 439107-94-5

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Description

6-Bromobenzofuran-2-carboxylic acid features a bromine substituent at the 6-position of the benzofuran core, enhancing electrophilic reactivity. The carboxylic acid group provides a handle for derivatization via amide or ester formation. This scaffold integrates readily into bioactive molecule synthesis and serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and heterocyclic drug candidates.

Application

6-Bromobenzofuran-2-carboxylic acid serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates derivatization via amide formation or esterification. The molecule exhibits good bench stability and compatibility with standard synthetic protocols, making it well-suited for iterative medicinal chemistry campaigns and scale-up applications.

General Information

  • CAS No. 439107-94-5
  • Cat. No. CS-0005588
  • Purity ≥97%
  • MDL No. MFCD03012913
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅BrO₃
  • Molecular Weight 241.04
  • Synonym(s) 6-bromo-2-Benzofurancarboxylic acid
  • SMILES O=C(C1=CC2=CC=C(Br)C=C2O1)O

Computational Chemistry Data

  • TPSA   50.44
  • LogP   2.8935
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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