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CS-W001157 4
Total: USD 88.00

3-(1,3-Dioxolan-2-yl)propanoic acid

  • CAS No. 4388-56-1

  • Cat. No. CS-W004427
  • Purity≥97%
  • MDL No.MFCD06209471

*For research and further manufacturing use only, not for direct human use.

3-(1,3-Dioxolan-2-yl)propanoic acid|CS-W004427

Structure of 4388-56-1

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General Information

  • CAS No. 4388-56-1
  • Cat. No. CS-W004427
  • Purity ≥97%
  • MDL No. MFCD06209471
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₄
  • Molecular Weight 146.14
  • Synonym(s) None
  • SMILES O=C(O)CCC1OCCO1

Description

3-(1,3-Dioxolan-2-yl)propanoic acid features a protected 1,3-dioxolane ring tethered to a propanoic acid side chain, enabling stable incorporation into synthetic sequences. This masked aldehyde precursor integrates seamlessly into multistep syntheses, offering controlled reactivity under standard conditions while maintaining bench stability and compatibility with diverse functional groups.

Application

3-(1,3-Dioxolan-2-yl)propanoic acid serves as a versatile building block in synthetic organic chemistry, enabling the introduction of a protected aldehyde functionality via controlled ring-opening. The 1,3-dioxolane moiety provides excellent bench stability and compatibility with a wide range of reaction conditions, while facilitating selective transformations under mild acidic or nucleophilic activation. Its functional group tolerance supports efficient incorporation into complex molecular architectures, including heterocyclic scaffolds and bioactive intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   0.2241
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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