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Structure of 4385-62-0
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4-(Pyridin-2-yl)benzoic acid features a rigid, planar architecture integrating a pyridine ring and a benzoic acid moiety, enabling strong π–π interactions and directional hydrogen bonding. This structural motif enhances solubility in polar organic solvents while maintaining stability under standard bench conditions, facilitating its use in scaffold diversification and metal coordination studies.
4-(Pyridin-2-yl)benzoic acid serves as a versatile building block for constructing biaryl scaffolds and heterocyclic systems in medicinal chemistry. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions, while the pyridine and benzene rings provide orthogonal sites for further functionalization. The compound exhibits good bench stability and facilitates efficient purification via recrystallization, making it well-suited for scalable synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: