Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-(4-(Trifluoromethoxy)phenyl)thiazol-2(3h)-imine

  • CAS No. 436151-95-0

  • Cat. No. CS-0268383
  • Purity≥97%
  • MDL No.MFCD03094299

*For research and further manufacturing use only, not for direct human use.

4-(4-(Trifluoromethoxy)phenyl)thiazol-2(3h)-imine|CS-0268383

Structure of 436151-95-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 436151-95-0
  • Cat. No. CS-0268383
  • Purity ≥97%
  • MDL No. MFCD03094299
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇F₃N₂OS
  • Molecular Weight 260.24
  • Synonym(s) 4-(4-Trifluoromethoxyphenyl)thiazol-2-ylamine
  • SMILES C1=C(C=CC(=C1)OC(F)(F)F)C2=CSC(=N)N2

Description

4-(4-(Trifluoromethoxy)phenyl)thiazol-2(3H)-imine features a trifluoromethoxy-substituted phenyl group linked to a thiazole-imine scaffold, delivering enhanced electron-withdrawing character and metabolic stability. This structure facilitates direct incorporation into bioactive heterocycles and enables efficient coupling in transition-metal-catalyzed transformations under standard conditions.

Application

4-(4-(Trifluoromethoxy)phenyl)thiazol-2(3H)-imine serves as a versatile building block for constructing thiazole-based heterocycles, enabling efficient access to biologically relevant scaffolds. Its trifluoromethoxy-substituted aryl group enhances metabolic stability and lipophilicity, while the imine functionality facilitates nucleophilic addition and condensation reactions under mild conditions. The compound exhibits excellent bench stability and compatibility with standard purification protocols, making it well-suited for medicinal chemistry campaigns and process-scale synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   48.87
  • LogP   3.12127
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 436151-95-0 sigma436151-95-0 manufacturer436151-95-0 price436151-95-0 structure436151-95-0 SDSbuy 436151-95-0436151-95-0 supplier436151-95-0 uses436151-95-0 molecular weightprice of 436151-95-0436151-95-0 chemical name formula of 436151-95-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label