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CS-W001157 4
Total: USD 88.00

2-Methoxypropionic acid

  • CAS No. 4324-37-2

  • Cat. No. CS-W004806
  • Purity≥97%
  • MDL No.MFCD00126928

*For research and further manufacturing use only, not for direct human use.

2-Methoxypropionic acid|CS-W004806

Structure of 4324-37-2

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General Information

  • CAS No. 4324-37-2
  • Cat. No. CS-W004806
  • Purity ≥97%
  • MDL No. MFCD00126928
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₃
  • Molecular Weight 104.11
  • Synonym(s) 2-Methoxypropanoic acid
  • SMILES COC(C)C(O)=O

Description

2-Methoxypropionic acid is a polar aprotic solvent featuring a methyl-substituted ester moiety, offering enhanced solubility for high-boiling organic compounds. This bench-stable reagent integrates seamlessly into synthesis workflows requiring controlled polarity and minimal nucleophilicity.

Application

2-Methoxypropionic acid serves as a versatile polar aprotic solvent and synthetic intermediate, enabling efficient esterifications and amide couplings. Its moderate boiling point and bench stability facilitate straightforward purification, while the orthoester functionality supports selective transformations in peptide synthesis and heterocycle construction.

Synthesis

  • Route1
    • null|null
      124-41-4
    • null|null
      598-72-1
    • ~10%
    • In-stock
      2-Methoxypropionic acid|CS-W004806
      4324-37-2

    References

    • BAYER PHARMACEUTICALS CORPORATION Patent: WO2006/133006 A2, 2006 ; Location in patent: Page/Page column 46-47 ;
  • Route2
    • null|null
      27871-49-4
    • null|null
      74-88-4
    • ~64%
    • In-stock
      2-Methoxypropionic acid|CS-W004806
      4324-37-2

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2009/109549 A1, 2009 ; Location in patent: Page/Page column 138-139 ;
  • Route3
    • null|null
      67-56-1
    • null|null
      124-41-4
    • null|null
      598-72-1
    • ~99%
    • In-stock
      2-Methoxypropionic acid|CS-W004806
      4324-37-2

    References

    • BAYER PHARMACEUTICALS CORPORATION Patent: WO2006/2383 A2, 2006 ; Location in patent: Page/Page column 49-50 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.1059
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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