1-(Thiazol-2-yl)ethanamine

Name: 1-(Thiazol-2-yl)ethanamine
Brand: ChemScene
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CAS No. 432047-36-4
Cat. No. CS-W008693
Purity≥97%
MDL No.MFCD02854206

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 432047-36-4

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Description

1-(Thiazol-2-yl)ethanamine features a thiazole ring linked to an ethylamine side chain, delivering a versatile scaffold for medicinal chemistry. The nitrogen-rich heterocycle enhances solubility and binding affinity, while the primary amine enables facile conjugation. This compound serves as a key building block in targeted drug discovery and bioconjugation workflows.

Application

1-(Thiazol-2-yl)ethanamine serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, offering a readily accessible amine handle ortho to a thiazole ring. Its bench-stable nature and compatibility with standard coupling reactions enable efficient construction of bioactive scaffolds, particularly in kinase inhibitor and antimicrobial agent development. Functional group tolerance facilitates downstream derivatization without significant side-reaction interference.

General Information

CAS No. 432047-36-4
Cat. No. CS-W008693
Purity ≥97%
MDL No. MFCD02854206
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₈N₂S
Molecular Weight 128.20
Synonym(s) 1-(2-Thiazolyl)ethylaMine
SMILES NC(C)C1=NC=CS1

Computational Chemistry Data

TPSA 38.91
LogP 1.1628
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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1-(Thiazol-2-yl)ethanamine

CAS No. 432047-36-4

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