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Guanosine 5'-diphosphate (sodium), 96% HPLC

  • CAS No. 43139-22-6

  • Cat. No. CS-0046283
  • Purity≥98%
  • MDL No.MFCD00027411

*For research and further manufacturing use only, not for direct human use.

Guanosine 5'-diphosphate (sodium), 96% HPLC|CS-0046283

Structure of 43139-22-6

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General Information

  • CAS No. 43139-22-6
  • Cat. No. CS-0046283
  • Purity ≥98%
  • MDL No. MFCD00027411
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄N₅NaO₁₁P₂
  • Molecular Weight 465.18
  • Synonym(s) GDP (sodium), Type I, 96% (HPLC)
  • SMILES O=P(OP(O)(O[Na])=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O1

Description

Regulating G protein conformational shifts via GDP/GTP exchange dynamics, Guanosine 5′-diphosphate sodium salt (CAS 43139-22-6) modulates intracellular signal transduction cascades and influences ATP-sensitive potassium channel gating in metabolic sensing

Application

Guanosine 5′-diphosphate sodium salt (CAS 43139-22-6) enables precise GTP-γ-35S functional assays by stabilizing active conformations of G-proteins during nucleotide exchange. It drives receptor-effector coupling studies with high fidelity. Researchers leverage this to monitor agonist-induced GTPγS binding in Y1 receptors and optimize recombinant protein expression systems through controlled nucleotide availability.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   255.4
  • LogP   -6.0807
  • H_Acceptors   13
  • H_Donors   6
  • Rotatable_Bonds   6

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