Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3,3,3-Trifluoropropane-1,2-diol

  • CAS No. 431-39-0

  • Cat. No. CS-0138549
  • Purity≥97%
  • MDL No.MFCD02183521

*For research and further manufacturing use only, not for direct human use.

3,3,3-Trifluoropropane-1,2-diol|CS-0138549

Structure of 431-39-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 431-39-0
  • Cat. No. CS-0138549
  • Purity ≥97%
  • MDL No. MFCD02183521
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅F₃O₂
  • Molecular Weight 130.06
  • Synonym(s) 2,3-Dihydroxy-1,1,1-trifluoropropane, 3,3,3-Trifluoropropylene glycol
  • SMILES OCC(O)C(F)(F)F

Description

3,3,3-Trifluoropropane-1,2-diol features a trifluoromethyl group flanking a geminal diol system, conferring enhanced stability and polarity. This combination enables efficient integration into fluorinated scaffolds for medicinal chemistry applications. The molecule exhibits favorable solubility in polar solvents and tolerates standard reaction conditions, streamlining access to bioactive intermediates.

Application

3,3,3-Trifluoropropane-1,2-diol serves as a stable, bench-ready building block for fluorinated scaffolds. Its vicinal diol functionality enables efficient epoxide formation and subsequent ring-opening reactions, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity—key attributes in medicinal chemistry. The compound exhibits good solubility and functional group tolerance, facilitating integration into multi-step syntheses of bioactive molecules.

Synthesis

  • Route1
    • null|null
      644994-85-4
    • Ethyl 3,3,3-trifluoro-DL-lactate|CS-0121308
      94726-00-8
    • ~77%
    • In-stock
      3,3,3-Trifluoropropane-1,2-diol|CS-0138549
      431-39-0

    References

    • Central Glass Company, Limited Patent: US2004/49076 A1, 2004 ; Location in patent: Page 5; 6 ;
  • Route2
    • null|null
      359-41-1
    • ~%
    • In-stock
      3,3,3-Trifluoropropane-1,2-diol|CS-0138549
      431-39-0

    References

    • Mitsui Chemicals, Inc. Patent: US6180800 B2, 2001 ;
  • Route3

    References

    • Wang; Lee; Li; Yang; Huang Electrochemistry Communications, 2010 , vol. 12, # 3 p. 386 - 389

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅲ
Hazard Statements : H225-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.0981
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3,3,3-Trifluoropropane-1,2-diol sigma3,3,3-Trifluoropropane-1,2-diol manufacturer3,3,3-Trifluoropropane-1,2-diol price3,3,3-Trifluoropropane-1,2-diol structure3,3,3-Trifluoropropane-1,2-diol SDSbuy 3,3,3-Trifluoropropane-1,2-diol3,3,3-Trifluoropropane-1,2-diol supplier3,3,3-Trifluoropropane-1,2-diol uses3,3,3-Trifluoropropane-1,2-diol molecular weightprice of 3,3,3-Trifluoropropane-1,2-diol3,3,3-Trifluoropropane-1,2-diol chemical name formula of 3,3,3-Trifluoropropane-1,2-diol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label