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Structure of 4302-52-7
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4-Ethynyl-1,2-dimethoxybenzene is a bench-stable, moisture-tolerant aryl alkyne featuring two methoxy groups that enhance solubility and electron density. This functionalized building block integrates readily into Sonogashira coupling reactions, enabling efficient access to conjugated architectures in materials science and medicinal chemistry applications.
4-Ethynyl-1,2-dimethoxybenzene serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to substituted biaryls and conjugated systems. The ethynyl group exhibits high reactivity in Sonogashira couplings, while the 1,2-dimethoxy substitution pattern provides excellent stability and solubility. This compound functions reliably in multi-step syntheses, offering predictable regiochemistry and compatibility with diverse functional groups under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: