5-Bromo-2-chloro-4,6-dimethylnicotinonitrile

Name: 5-Bromo-2-chloro-4,6-dimethylnicotinonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 42951-71-3
Cat. No. CS-W003116
Purity≥98%
MDL No.MFCD03791216

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-chloro-4,6-dimethylnicotinonitrile|CS-W003116

Structure of 42951-71-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Bromo-2-chloro-4,6-dimethylnicotinonitrile features a sterically hindered pyridine core with complementary halogen and nitrile functionalities. This configuration enables direct coupling in cross-coupling reactions, delivering complex heterocycles under standard conditions. The molecule exhibits bench-stable handling and moisture-tolerant reactivity, streamlining integration into synthetic workflows for medicinal chemistry and materials development.

Application

5-Bromo-2-chloro-4,6-dimethylnicotinonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis. Its ortho-halogenated pyridine core enables palladium-catalyzed cross-coupling reactions with high efficiency. The nitrile group provides a handle for further functionalization, while the methyl substituents enhance metabolic stability and modulate electronic properties. Bench-stable and compatible with standard purification methods, it facilitates streamlined access to complex heterocyclic scaffolds.

General Information

CAS No. 42951-71-3
Cat. No. CS-W003116
Purity ≥98%
MDL No. MFCD03791216
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆BrClN₂
Molecular Weight 245.50
Synonym(s) 5-bromo-2-chloro-4,6-dimethylpyridine-3-carbonitrile
SMILES CC1=C(Br)C(C)=NC(Cl)=C1C#N

Computational Chemistry Data

TPSA 36.68
LogP 2.98602
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

42951-71-3 sigma42951-71-3 manufacturer42951-71-3 price42951-71-3 structure42951-71-3 SDSbuy 42951-71-342951-71-3 supplier42951-71-3 uses42951-71-3 molecular weightprice of 42951-71-342951-71-3 chemical name formula of 42951-71-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-2-chloro-4,6-dimethylnicotinonitrile

CAS No. 42951-71-3

Recommended Products